Factory Supply Selumetinib Azd6244 Powder CAS 606143-52-6 for Anticancer

 Factory Supply Selumetinib AZD6244 Powder CAS 606143-52-6 for Anticancer

I have something to say: customers, we always put integrity in the first place, honest treatment of every customer.Our mission is to make sure every customers get what make they pay successfully.

We are Guangzhou Quanao Chemical Co.,Ltd. the leading manufacture come from China,who supply Powder,Liquid (Oral and Injectable) ,Peptides,Local anesthetics,Sarms,Fat Loss and other chemical raw materials.

Due to the limitation of the website, many products are not released. If you don't find what you are interested in, you can contact me directly and I will offer you what you are finding.






My card:





Minimum Order Quantity:Negotiation

Price:Negotiation

Packaging Details:Discreet ways of packing for Customs pass guaranteed(1kg foil bag)

Leading time:Within 8hours after payment.(PS: USA based delievry could be available.)

Delivery time:Within 5working days after payment.

Payment method:Western Union,Money Gram,Bank Transfer,Bitcoin.

Supply Ability:100ton Per Month

Shipment Method: UPS DHL Fedex TNT EMS HKEMS HongKong post EUB ETK

Basic information:

Chemical name: Selumetinib
MF: C17H15BrClFN4O3
MW: 457.685
CAS: 606143-52-6
Appearance: White powder
Purity: 99%
Package: 100g/foil bag

Description:

Selumetinib is an orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent inhibitor of mitogen-activated protein kinase kinase (MEK or MAPK/ERK kinase) 1 and 2. MEK 1 and 2 are dual specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various cancer cells, and are drivers of diverse cellular responses, including proliferation. Inhibition of both MEK1 and 2 by selumetinib prevents the activation of MEK1/2 dependent effector proteins and transcription factors, thereby leading to an inhibition of cellular proliferation in various cancers.

Selumetinib is under investigation for the treatment of Carcinoma, Thymic, Non-Small Cell Lung Cancer, and Carcinoma, Small Cell Lung. AZD6244 has been investigated for the treatment and basic science of Melanoma, Solid Tumours, Breast Cancer, Non Small Cell Lung Cancer, and Non Small Cell Lung Carcinoma, among others.

Mechanism of action:

The gene BRAF is part of the MAPK/ERK pathway, a chain of proteins in cells that communicates input from growth factors. Activating mutations in the BRAF gene, primarily V600E (meaning that the amino acid valine in position 600 is replaced by glutamic acid), are associated with lower survival rates in patients with papillary thyroid cancer. Another type of mutation that leads to undue activation of this pathway occurs in the gene KRAS and is found in NSCLC. A possibility of reducing the activity of the MAPK/ERK pathway is to block the enzyme MAPK kinase (MEK), immediately downstream of BRAF, with the drug selumetinib. More specifically, selumetinib blocks the subtypes MEK1 and MEK2 of this enzyme.
 

Packing:

1.Food bag packing( Disguised package)

Usually products are send in discreet way,based on our rich in shipping products to every countries,we usually use disguised way.
The photo of food disguised package for your reference,which has passed through every countries smoothly,products are packed well in  food box,which mixed with real visible chinese food,and in the express bill we will declare food and sample,customs just think it chinese food and release it.

2. Change the name to ship  your parcel(Foil bag)










Our advantage:
 
Professional Manufacture: GUANGZHOU Quanao CHEMICAL CO,LTD is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D,producing, operating and marketing into an organic whole.

Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
 
Payment Method: Western Union,Money Gram,T/T.Bitcoin.

Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.
 
Discreetly Packing: Safe and professional disguised package can be guaranteed.
 
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.

High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. 


Customers Feedbacks:

1.I have received my products , you package is do discreet and perfect , it really amazed me.I will order more from you as soon as possible.Thanks a lot.
--------------Robert--Australia

2.I have cooperated with you for many times ,the quality is so great ,will stick with you for long-term business relationship. Thank you.
-----------Richard---American

3.You have great ability to handle well with customs issues, the quality and price satisfy me,I will be loyal to you. Thank you.

------------Anil---Canada






No matter you become a customer to me or not at last, you are welcome to inquire from me!
Thank you!
Crystal (Miss) (^_^)

We supply customers the best quality, considerate service, reasonable price, safe and fast shipping.
100% guaranteeing customs pass,
200% supporting re-sending policy.

We can promise you:It must be be safe and guaranteed!
Any questions pls do not hesitate to contact me,I'm always here to help you!


Welcome to our online store , please feel free to contact me if you're interested in our items . We are a big preffesional supplier in China ,there are high quality raw powders , painless injectable oils and pharmaceutical peptides . Wholesale price will be sent to you when you want to make long term business with us . Special package picture and uniue channel will share with you within our cooperations ,10kg ,25kg and more powders are available from us to send .

Our products have exported to Germany,Brazil ,USA, , Spain, UK,  France, Canada, Mexico,Poland, Russia,  Australia,   Norway,Finland,  and many other countries, over 100kgs each month  
 

TIPS: How to Place An Order?

If you are ready to place an order, please use the contact form "Inquiry Now" on the page or send an email directly with product names and quantity. 
Crystal aims to reply you within 1 hour to 12 hours since you send the message. She will handle your order.
Please don't forget to add Crystal' s email address to your address book so She'll be sure to land in your inbox.

 

Related products

 

 

 Factory Supply Selumetinib AZD6244 Powder CAS 606143-52-6 for Anticancer

I have something to say: customers, we always put integrity in the first place, honest treatment of every customer.Our mission is to make sure every customers get what make they pay successfully.

We are Guangzhou Quanao Chemical Co.,Ltd. the leading manufacture come from China,who supply Powder,Liquid (Oral and Injectable) ,Peptides,Local anesthetics,Sarms,Fat Loss and other chemical raw materials.

Due to the limitation of the website, many products are not released. If you don't find what you are interested in, you can contact me directly and I will offer you what you are finding.






My card:





Minimum Order Quantity:Negotiation

Price:Negotiation

Packaging Details:Discreet ways of packing for Customs pass guaranteed(1kg foil bag)

Leading time:Within 8hours after payment.(PS: USA based delievry could be available.)

Delivery time:Within 5working days after payment.

Payment method:Western Union,Money Gram,Bank Transfer,Bitcoin.

Supply Ability:100ton Per Month

Shipment Method: UPS DHL Fedex TNT EMS HKEMS HongKong post EUB ETK

Basic information:

Chemical name: Selumetinib
MF: C17H15BrClFN4O3
MW: 457.685
CAS: 606143-52-6
Appearance: White powder
Purity: 99%
Package: 100g/foil bag

Description:

Selumetinib is an orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent inhibitor of mitogen-activated protein kinase kinase (MEK or MAPK/ERK kinase) 1 and 2. MEK 1 and 2 are dual specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various cancer cells, and are drivers of diverse cellular responses, including proliferation. Inhibition of both MEK1 and 2 by selumetinib prevents the activation of MEK1/2 dependent effector proteins and transcription factors, thereby leading to an inhibition of cellular proliferation in various cancers.

Selumetinib is under investigation for the treatment of Carcinoma, Thymic, Non-Small Cell Lung Cancer, and Carcinoma, Small Cell Lung. AZD6244 has been investigated for the treatment and basic science of Melanoma, Solid Tumours, Breast Cancer, Non Small Cell Lung Cancer, and Non Small Cell Lung Carcinoma, among others.

Mechanism of action:

The gene BRAF is part of the MAPK/ERK pathway, a chain of proteins in cells that communicates input from growth factors. Activating mutations in the BRAF gene, primarily V600E (meaning that the amino acid valine in position 600 is replaced by glutamic acid), are associated with lower survival rates in patients with papillary thyroid cancer. Another type of mutation that leads to undue activation of this pathway occurs in the gene KRAS and is found in NSCLC. A possibility of reducing the activity of the MAPK/ERK pathway is to block the enzyme MAPK kinase (MEK), immediately downstream of BRAF, with the drug selumetinib. More specifically, selumetinib blocks the subtypes MEK1 and MEK2 of this enzyme.
 

Packing:

1.Food bag packing( Disguised package)

Usually products are send in discreet way,based on our rich in shipping products to every countries,we usually use disguised way.
The photo of food disguised package for your reference,which has passed through every countries smoothly,products are packed well in  food box,which mixed with real visible chinese food,and in the express bill we will declare food and sample,customs just think it chinese food and release it.

2. Change the name to ship  your parcel(Foil bag)










Our advantage:
 
Professional Manufacture: GUANGZHOU Quanao CHEMICAL CO,LTD is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D,producing, operating and marketing into an organic whole.

Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
 
Payment Method: Western Union,Money Gram,T/T.Bitcoin.

Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.
 
Discreetly Packing: Safe and professional disguised package can be guaranteed.
 
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.

High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. 


Customers Feedbacks:

1.I have received my products , you package is do discreet and perfect , it really amazed me.I will order more from you as soon as possible.Thanks a lot.
--------------Robert--Australia

2.I have cooperated with you for many times ,the quality is so great ,will stick with you for long-term business relationship. Thank you.
-----------Richard---American

3.You have great ability to handle well with customs issues, the quality and price satisfy me,I will be loyal to you. Thank you.

------------Anil---Canada






No matter you become a customer to me or not at last, you are welcome to inquire from me!
Thank you!
Crystal (Miss) (^_^)

We supply customers the best quality, considerate service, reasonable price, safe and fast shipping.
100% guaranteeing customs pass,
200% supporting re-sending policy.

We can promise you:It must be be safe and guaranteed!
Any questions pls do not hesitate to contact me,I'm always here to help you!


Welcome to our online store , please feel free to contact me if you're interested in our items . We are a big preffesional supplier in China ,there are high quality raw powders , painless injectable oils and pharmaceutical peptides . Wholesale price will be sent to you when you want to make long term business with us . Special package picture and uniue channel will share with you within our cooperations ,10kg ,25kg and more powders are available from us to send .

Our products have exported to Germany,Brazil ,USA, , Spain, UK,  France, Canada, Mexico,Poland, Russia,  Australia,   Norway,Finland,  and many other countries, over 100kgs each month  
 

TIPS: How to Place An Order?

If you are ready to place an order, please use the contact form "Inquiry Now" on the page or send an email directly with product names and quantity. 
Crystal aims to reply you within 1 hour to 12 hours since you send the message. She will handle your order.
Please don't forget to add Crystal' s email address to your address book so She'll be sure to land in your inbox.

 

Related products