High Purity Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol

High Purity Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol


Product Name: Ezetimibe 
Synonyms: 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;EZETIMIBE;ZETIA;Ezitimibe∬
EzetimibeC24H21F2N03;(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235;1-(4-Flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone;Ezetimide 
CAS: 163222-33-1 
MF: C24H21F2NO3 
MW: 409.43
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;
Pharmaceuticals;Final material;API;Isotope;CEDAX;Cardiovascular APIs;Ezetimibe
Melting point  164-166°C 
Storage temp.  RT.
Chemical Properties White Solid 
Usage An antihyperlipoproteinemic. A Cholesterol absorption inhibitor 
Usage antibacterial 
Usage A cholesterol transport inhibitor that binds to NPC1L1 
Usage For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia . 


What is ezetimibe ?
 

Cholesterol-lowering drugs 

Ezetimibe,jointly developed by Schering-Plough and Merck companies ,is the first selective cholesterol absorption inhibitor, the product is first approved by the US FDA listed as selective cholesterol absorption inhibitor class of drugs. 

Ezetimibe is a new selective cholesterol absorption inhibitor, it is also the first selective inhibitor of intestinal cholesterol absorption, and its mechanism of action is different from other lipid-lowering agents (such as: statins, bile acid sequestrants, phenoxy acid derivative thereof cattle and plant sterol ester compound), the product ,through binding with the intestinal brush border membrane vesicle membrane protein (relative molecular mass 145X103), inhibits intestinal absorption of cholesterol which is from diet and transported to the intestine via the bile tract , reduces serum and liver cholesterol. Different from acid chelating agent ,ezetimibe does not affect cholesterol esters, other steroids (such as bezoar acid), triglycerides and fat-soluble vitamin absorption. Its pharmacological effects have nothing to do with acetyl coenzyme A- cholesterol acetyltransferase (ACAT) inhibiting and LDL receptors (scavenger receptor) expression . After being absorbed in the liver , ezetimibe combined with glucuronic acid by enterohepatic circulation,is almost specifically targeting to the small intestine mucosa. It can be used alone or in combination with HMG-CoA reductase inhibitors (statins) jointly applied to the treatment of primary (heterozygous familial and non-familial) hypercholesterolemia, homozygous familial hypercholesterolemia (HoFH) homozygous sitosterol hyperlipidemia (hyperlipidemia or phytosterols).

Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin or Inegy) when statins alone do not control cholesterol.


Frequently Asked Questions :

Question , What is mean "semi-finished injection oil "

                     Our oil has mixed and heat well . Customer will filter with last one step when you receive the package .It is easy to operate ,we will teach you how to do if you need .

                 Semi-finished injection oil is much cheaper than finished oil ,good business to make more money , cheap ,safe for personal suage .

Question 1 , How do you pack the order ?

                Discreet package , the packing suits you best would be choosen to cross customs safely

Question 2, What is your shipping method

                  Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail

 Question 3, if my order seized by custom ,what do you do ?
                       
                  Resending police if the tracking number do not update online or it sezied by custom

  Questions 4, What is your payment accept 
 
                     Safe and fast payment : Western Union ,Money Gram ,T/T ,Bitcoin

    Questions 5, Will you supply tracking number 
             
              Yes ,we supply tracking number for following . In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days 

   Question 6, How many times will it take to my country after I do the payment

             In general ,fastest with 3-5 business , slowest 5-7 business days High Purity Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol


Product Name: Ezetimibe 
Synonyms: 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;EZETIMIBE;ZETIA;Ezitimibe∬
EzetimibeC24H21F2N03;(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235;1-(4-Flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone;Ezetimide 
CAS: 163222-33-1 
MF: C24H21F2NO3 
MW: 409.43
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;
Pharmaceuticals;Final material;API;Isotope;CEDAX;Cardiovascular APIs;Ezetimibe
Melting point  164-166°C 
Storage temp.  RT.
Chemical Properties White Solid 
Usage An antihyperlipoproteinemic. A Cholesterol absorption inhibitor 
Usage antibacterial 
Usage A cholesterol transport inhibitor that binds to NPC1L1 
Usage For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia . 


What is ezetimibe ?
 

Cholesterol-lowering drugs 

Ezetimibe,jointly developed by Schering-Plough and Merck companies ,is the first selective cholesterol absorption inhibitor, the product is first approved by the US FDA listed as selective cholesterol absorption inhibitor class of drugs. 

Ezetimibe is a new selective cholesterol absorption inhibitor, it is also the first selective inhibitor of intestinal cholesterol absorption, and its mechanism of action is different from other lipid-lowering agents (such as: statins, bile acid sequestrants, phenoxy acid derivative thereof cattle and plant sterol ester compound), the product ,through binding with the intestinal brush border membrane vesicle membrane protein (relative molecular mass 145X103), inhibits intestinal absorption of cholesterol which is from diet and transported to the intestine via the bile tract , reduces serum and liver cholesterol. Different from acid chelating agent ,ezetimibe does not affect cholesterol esters, other steroids (such as bezoar acid), triglycerides and fat-soluble vitamin absorption. Its pharmacological effects have nothing to do with acetyl coenzyme A- cholesterol acetyltransferase (ACAT) inhibiting and LDL receptors (scavenger receptor) expression . After being absorbed in the liver , ezetimibe combined with glucuronic acid by enterohepatic circulation,is almost specifically targeting to the small intestine mucosa. It can be used alone or in combination with HMG-CoA reductase inhibitors (statins) jointly applied to the treatment of primary (heterozygous familial and non-familial) hypercholesterolemia, homozygous familial hypercholesterolemia (HoFH) homozygous sitosterol hyperlipidemia (hyperlipidemia or phytosterols).

Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin or Inegy) when statins alone do not control cholesterol.


Frequently Asked Questions :

Question , What is mean "semi-finished injection oil "

                     Our oil has mixed and heat well . Customer will filter with last one step when you receive the package .It is easy to operate ,we will teach you how to do if you need .

                 Semi-finished injection oil is much cheaper than finished oil ,good business to make more money , cheap ,safe for personal suage .

Question 1 , How do you pack the order ?

                Discreet package , the packing suits you best would be choosen to cross customs safely

Question 2, What is your shipping method

                  Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail

 Question 3, if my order seized by custom ,what do you do ?
                       
                  Resending police if the tracking number do not update online or it sezied by custom

  Questions 4, What is your payment accept 
 
                     Safe and fast payment : Western Union ,Money Gram ,T/T ,Bitcoin

    Questions 5, Will you supply tracking number 
             
              Yes ,we supply tracking number for following . In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days 

   Question 6, How many times will it take to my country after I do the payment

             In general ,fastest with 3-5 business , slowest 5-7 business days

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