New findings: Artemisinin helps treat congenital deafness
June 14, 2019 Source: Xinhuanet
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Xinhua News Agency, Beijing, June 13th, Chinese artichokes discovered by Chinese scientists based on Chinese medicine literature research have become "anti-malaria stars." A new study found that in addition to treating malaria, artemisinin may also help in the treatment of congenital deafness caused by mutations in specific genes.
The hair cells in the ear are the key cells in many animal balance systems and auditory systems. They can transform sound waves into signals that can be transmitted by nerves. The brain receives these signals and then "translates" them into useful information. However, a specific genetic mutation can cause hair cells to lose function, leading to deafness, balance disorders, and the like.
Researchers at the University of the United States in the United States reported that they used the zebrafish with this genetic mutation as an experimental object and found that artemisinin helps to reconstruct the auditory cell function of the inner ear. Produces more useful proteins in the inner ear of the zebrafish, helping the hair cells re-establish an auditory connection.
According to reports, whether to maintain balance and accurately sense the flow of water during swimming is the key to the survival of zebrafish, and these capabilities require hair cells to function. In this study, the zebrafish survival rate of genetic mutations increased from 5% to 45% after artemisinin treatment.
Kumar Alagrama, one of the authors and an assistant professor at Case Western Reserve University, said that artemisinin is expected to be used to alleviate human problems such as deafness caused by specific genetic mutations. In the future, it can also be used to study other sensory problems caused by genetic problems. obstacle.
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