Progress in non-invasive measurement of blood glucose can be quickly and continuously monitored by human blood glucose using optical technology

Progress in non-invasive measurement of blood glucose can be quickly and continuously monitored by human blood glucose using optical technology

December 3, 2018 Source: Health News Author: Li Zhe

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Professor Xu Kexin from Tianjin University has made new progress in the development of non-invasive blood glucose measurement instruments using optical technology to achieve non-invasive, rapid and continuous monitoring of human blood glucose levels. Related research results were published in the 11th issue of Biomedical Optics Express this year.

At present, diabetic patients use acupuncture to take blood to measure blood sugar levels, pain and infection. According to reports, the human body generally eats food, blood sugar levels will peak in about 1 hour, return to normal levels after 2 hours to 3 hours. During this period, changes in blood glucose can cause changes in the absorption and scattering of light from the skin. These optical signals can indirectly reflect the blood sugar level of the human body. The feasibility of this measurement method has been widely verified by scholars at home and abroad. Since the 1980s, research institutions around the world have been investing in related instruments, but no successful test instruments have been available at this stage.

In order to reduce the disturbance of human-machine interface and random variation of skin and eliminate individual differences, Xu Kexin team creatively proposed a new technology using multi-position circular receiving spectral signal and differential data processing to suppress body temperature fluctuation, skin sweating, human-machine interface. The influence of interference factors such as changes greatly improved the measurement accuracy. The team also proposed a new technology for spectral measurement based on special measurement positions such as floating reference points and scattering reference points for the first time to suppress skin state changes or individual differences. The impact of the measurement. These new measurement technologies are among the world's leading and have been granted two US patents (and also granted Chinese patents) between 2017 and 2018. At present, the non-invasive blood glucose monitoring instrument developed by the team has successfully realized the curve of continuous monitoring of blood glucose changes within 2 hours to 3 hours after eating. The detection error level is about 0.5 millimoles per liter to 1 millimoles per liter, and it is expected to pass. Wearable devices enable non-invasive, rapid, and continuous monitoring of blood sugar levels in the human body.

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