The nutritional value of dried whitebait
Dried whitebait is a high-protein, low-fat food that is suitable for patients with hyperlipidemia. Chinese medicine believes that it is sweet and flat, good to fill the spleen and stomach, and can Xuanfei, benefit water, can cure spleen and stomach weakness, lung deficiency cough, consumptive disease. The general population can eat, especially for physical weakness, lack of nutrition, indigestion who eat; suitable for hyperlipidemia, weak spleen and stomach, lung deficiency cough, consumptive embolism.
The therapeutic effect of dried whitebait
Sweet, flat, spleen, stomach; have lungs and cough, good fill the spleen and stomach, Xuanfei, benefit the role of water; can cure spleen and stomach weakness, lung deficiency cough, consumptive disease.
pharmacological action
Oxytetracycline has broad-spectrum antiviral effect on microorganisms. It is a rapid bacteriostatic agent. It has bactericidal effect on some bacteria at high concentration. Its mechanism is that the drug can specifically bind to the a position of ribosomal 30S subunit and prevent the connection of aminoacyl tRNA at this position, so as to inhibit the growth of peptide chain and affect the protein synthesis of bacteria or other pathogenic microorganisms. Oxytetracycline has strong antibacterial activity against Staphylococcus aureus, pneumococcus, Streptococcus pyogenes, Neisseria gonorrhoeae, meningococci, Escherichia coli, aerogenic bacteria, Shigella, Yersinia and Listeria monocytogenes; In addition, oxytetracycline also has strong effects on Rickettsia, mycoplasma, chlamydia and actinomycetes. [3]
Pharmacokinetics
The oral absorption of oxytetracycline hydrochloride is incomplete (about 30% - 58%), and the distribution volume is about 0.9-1.9l/kg. After a single dose of 1g, the peak blood concentration was about 3.9mg/l. After absorption, the drug is widely distributed, which can penetrate into pleural effusion and peritoneal effusion, or enter fetal blood circulation through placental barrier, but it is not easy to pass through blood cerebrospinal fluid barrier, so the drug concentration in cerebrospinal fluid is low. Oxytetracycline can also be distributed in liver, spleen, bone marrow, bone, dentin and enamel, and the drug can also reach a high concentration in milk. The binding rate of oxytetracycline protein is about 20% - 35%. The half-life of patients with normal renal function is 6-10h, the half-life of patients with renal insufficiency is prolonged, and the half-life of patients without urine can reach 47-66h. Drugs are mainly excreted through glomerular filtration, 70% of the dosage can be excreted within 24 hours of administration, and a small amount of drugs are excreted through bile and feces. Hemodialysis can remove 10% - 15% of drugs. [4]
indication
1. Oxytetracycline can be used as an optional drug for the treatment of the following diseases:
(1) Rickettsia disease, including epidemic typhus, endemic typhus and tsutsugamushi disease; [3]
(2) Mycoplasma pneumoniae infection; [3]
(3) Chlamydia infection, including psittacosis, inguinal granuloma (venereal lymphogranuloma), nonspecific urethritis, salpingitis and trachoma; (4) Regressive fever; [3]
(5) Brucellosis (in combination with aminoglycosides); [3]
(6) Cholera; [3]
(7) plague (combined with aminoglycoside drugs); [3]
(8) Rabbit fever. [3]
2. Oxytetracycline can be used to treat tetanus, gas gangrene, Yasi, syphilis, gonorrhea and leptospirosis allergic to penicillin antibiotics.
3. Oxytetracycline can also be used to treat respiratory tract, biliary tract, urinary tract, skin and soft tissue infections caused by sensitive bacteria. [3]
4. Oxytetracycline can also be used in the treatment of acne. [3]
contraindication
Allergic to oxytetracycline or other tetracyclines. [3]
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