One in nine men in the United States is infected with oral HPV, which can cause head and neck cancer
Release date: 2017-10-24
Recently, according to a report published by the Annals of Internal of Medicine, the study reported that about one in nine (about 11 million) men in the United States are infected with oral human papillomavirus (HPV), which is easy. Lead to the occurrence of head and neck tumors.
Researchers at the University of Florida and the National Institutes of Health (NIH) have recently conducted a study to determine the prevalence of HPV infection in men and women in the mouth and genitals.
The study found that nearly one-ninth of American men between the ages of 18 and 69 were infected with HPV, and men with multiple sexual partners or those with homosexual or homosexual oral sex were at risk of oral HPV. Higher. In addition, HPV virus is also infected through genital contact.
Research data in the report
Ashish Deshmukh, a research assistant professor at the University of Florida School of Public Health and Health, and colleagues studied CDC (US Centers for Disease Control and Prevention) data analysis and found that:
During 2011-2014, nearly 11.5% of men and 3.2% of women in the United States were infected with oral HPV;
Nearly 2 million people have high-risk HPV16 subtypes, a virus that causes most cancers. Men are six times more likely than women.
Among male and female patients with same-sex partners, HPV infection rates were 12.7% and 3.6%, respectively;
Among men with two or more same-sex couples, the prevalence of HPV infection was 22.2%;
The highest predictive probability of high-risk oral HPV infection is black participants, those who smoke more than 20 cigarettes a day, those who smoke cannabis, and those who have long-term sexual partners.
What is oral HPV?
The same type of HPV that infects the genital area can infect the mouth and throat. HPV found in the mouth and throat is called oral HPV. According to reports, the cancer caused by HPV is usually in the back of the mouth, including the root of the tongue, the back of the throat, the tonsils and other parts. Cancers that are not associated with HPV generally occur in front of the tongue, and include the bottom of the mouth, the inside of the cheeks, and the gums.
What subtypes does HPV have?
There are many subtypes of HPV, and more than 120 have been confirmed so far. About 40 HPVs are associated with female genital tract infections and lesions. People are classified into high-risk and low-risk types according to the carcinogenicity of HPV. High-risk HPV mainly includes 16, 18, 3l, 33, 39, 45, 51, 52, 56, 58, 59, 68, etc.; low-risk HPV mainly has 6, 1l, 42, 43, and 44 types.
Studies have shown that HPV-16 and HPV-18 HPV viruses and some of the less common HPV infections can not only cause cervical cancer, but also may cause vaginal cancer, vulvar cancer, anal cancer and laryngeal cancer.
Progress in research on HPV and head and neck tumors
Head and neck cancer is a cancer that starts from the tissues and organs of the head and neck. They include cancers of the throat, lips, mouth, nose and salivary glands. Lead researcher Ashish Deshmukh said: "The incidence of this cancer has increased by 300% in the past 20 years."
The main signs and symptoms of head and neck tumors may include persistent sore throat, hoarseness, swollen lymph nodes, swallowing pain, and unexplained weight loss. Some people have no signs or symptoms.
Tobacco and alcohol have long been recognized as major risk factors for head and neck cancer. In 1983, Syrjanen and other scholars detected HPV in patients with oral squamous cell carcinoma, suggesting that HPV may be another cause of malignant tumors of the head and neck. Cause. In a 2004 survey, 72% of patients with laryngeal cancer were positive for HPV. HPV infection has surpassed excessive drinking and smoking, becoming the leading cause of laryngeal cancer. Unlike traditional tobacco and alcohol, the pathogenesis of HPV is wild-type p53 gene, low expression of pRb gene and overexpression of p16.
How to reduce the risk of contracting oral HPV?
What are the best ways to prevent oral HPV? The use of condoms or dental dams during sexual intercourse may generally reduce the chance of oral HPV interpersonal communication during oral sex. HPV vaccine can also prevent oropharyngeal cancer. CDC recommends that men should also be vaccinated against HPV to prevent genital warts, anal cancer and laryngeal cancer. The age of vaccination can be up to 26 years old.
Through the study, researchers hope to find better management methods to screen for disease and vaccinate HPV vaccines to people of all ages.
references
1. "1 in 9 American Men Infected With Oral HPV"
Https://medlineplus.gov/news/fullstory_169110.html
2. "HPV and Oropharyngeal Cancer"
Https://
3.Annalsof Internal of Medicine: "Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance With Genital Human Papillomavirus Infection, NHANES 2011 to 2014"
Http://annals.org/aim/article/2657698/oral-human-papillomavirus-infection-differences-prevalence-between-sexes-concordance-genital
Source: Medical Valley
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