The world's first placental stem cell transplantation was successful

Release date: 2015-07-17

The Affiliated Hospital of the Academy of Military Medical Sciences (the 307th Hospital of the People's Liberation Army) announced this afternoon that after 16 months of postoperative observation, the world's first placental hematopoietic stem cells combined with cord blood stem cell transplantation for the treatment of severe aplastic anemia were first carried out by the Chen Hu team. success.

Attending doctor Qi Jiangwei introduced that in 2013, a 9-year-old rural girl from Qian’an City, Hebei Province, was admitted to hospital for anemia due to aplastic anemia. In March 2014, after obtaining the consent of the parents of the children, 307 Hospital extracted hematopoietic stem cells and umbilical cord hematopoietic stem cells from the girl's newly born sister placenta for transplantation. The patient was discharged after rehabilitation, and the hematopoietic function returned to normal and the health was stable. .

Chen Hu, director of the Hematopoietic Stem Cell Transplantation Department, said that umbilical cord hematopoietic stem cells have the advantages of weak immunogenicity and low requirements for original matching, and the incidence of transplant-versus-host disease is low, but the number is too small to be easily implanted. Placental tissue contains a large number of hematopoietic stem cells. By separating hematopoietic stem cells from the placenta, it can effectively compensate for the deficiency of the number of umbilical cord stem cells. The joint transplantation of the two is the first report in the world.

Source: People's Daily

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