Chinese scientists successfully prepared multi-functional tumor diagnosis and treatment integrated nanosystem
Recently, the Strong Magnetic Field Science Center of Hefei Institute of Material Science, Chinese Academy of Sciences, and the National Laboratory of Hefei Microscale Physical Science of China University of Science and Technology, Chen Yunwang, and the Associate Professor of Life Sciences, Guo Zhen and Deputy Chief Physician of Anhui Medical University. Wang Haibao's research team collaborated to prepare a new type of multi-functional tumor diagnosis and treatment integrated nanosystem. The diagnosis and treatment of cancer has always been a problem in the scientific community, and Theranostics combines the diagnosis and treatment in an organically synchronized manner to achieve simultaneous diagnosis. X-ray tomography (CT) and positron emission tomography (PET), which are commonly used in clinical practice, can cause great radiation damage to the human body. In contrast, magnetic resonance imaging (MRI) and fluorescence imaging (FOI) are favored for their unique non-invasive and non-invasive advantages.
In fluorescence imaging applications, near-infrared light (wavelengths of 700-1000 nm) has good bio-tissue penetration, so high resolution and imaging results can be obtained. At present, because of surgery and radiotherapy and chemotherapy, there may be metastasis and recurrence, and the side effects are relatively large. Photothermal therapy is an emerging potential treatment. It uses a photothermal agent that responds to near-infrared light and converts light energy into heat energy. It can be used to treat the lesions, irradiate the lesions, and effectively kill cancer cells. Ground damage to normal tissue. If you can combine multiple diagnostic methods with multiple treatments, you will get better results.
Based on the previous synthesis of Mn3[Co(CN)6]2@SiO2@Ag nanoparticles, researchers have developed a system for integrated application of tumor diagnosis and treatment. The nanoparticle core-shell cube has T1/T2 dual-mode nuclear magnetic resonance imaging capability, and also has full-color (red, green, and blue) fluorescence imaging and 720 nm two-photon imaging capability. The internal porous metal organic framework (MOFs) structure Mn3[Co(CN)6]2 has the ability to load the anticancer drug doxorubicin. After the surface is loaded with silver nanoparticles, the two-photon imaging capability of the material is improved by 1.85 times. At the same time, due to the plasma absorption performance of the silver nanoparticles, the material has a photothermal conversion capability of 808 nm laser response, and the cell experiment shows the multifunctional function. The integrated treatment system has synergistic photothermal-chemotherapy capabilities.
The results were published online in Small Mn3[Co(CN)6]2@SiO2@Ag Core–Shell Nanocube: Enhanced Two-Photon Fluorescence and Magnetic Resonance Dual-Modal Imaging-Guided Photothermal and Chemo-therapy. 11, 5956–5967).
Preparation process of Mn3[Co(CN)6]2@SiO2@Ag particles and endocytic particles of cancer cells and diagnosis and treatment process
How to choose a solar Camera?
1. Select a low-power controller. The controller will work 24 hours a day. If its power consumption is large, it will consume part of the power. A good choice is a controller that consumes less than 1 mA.
2. Select a controller with high charging efficiency. The controller of the MCT charging mode can automatically track the high current of the panel. Especially in winter or periods of insufficient light, the efficiency of MCT charging mode is about 20% higher than other charging modes.
3. Select the controller for bidirectional power regulation. Controllers with power regulation have been widely promoted. When there are few pedestrians at night, one-way or two-way lighting can be automatically turned off to save electricity. It can also adjust the power of the LED lights.
In addition to the above power-saving functions, attention should also be paid to the protection functions of the controller for components such as batteries. In addition, when setting the under-voltage protection value of the controller, try to adjust the under-voltage protection value to ≥ to prevent the battery from over-discharging.
,Outdoor Security 4G Solar Camera purchasers from worldwide to visit our site.
4G Solar Camera,Solar Camera Wifi,Solar Camera Outdoor,Outdoor Security 4G Solar Camera
Shenzhen Fuvision Electronics Co., Ltd. , https://www.outdoorsolarcamera.com