Harvard University research team develops 3D printed cardiac organ chips

Washington, October 24th, Harvard University's John Paulson School of Engineering and Applied Sciences (SEAS) released a press release on the 24th, saying that a research team at the college developed a new 3D printing technology that can be printed with integrated transmission. Sensitive function of the organ chip. The first time they print out a heart chip that can be quickly assembled and customized to make data collection easier, opening up a new path for drug research. Related research was published in the journal Nature·Materials.

Organ chip is considered to be a revolutionary technology in life science research, and has broad application prospects in the fields of medicine, scientific research and clinical drug design. However, the manufacture and data collection of organ chips is not an easy task. Not only is the manufacturing environment extremely demanding, but the manufacturing process is also very complicated, costly and time consuming.

There are many "small wells" on the chip.

This time, the SEAS research team used advanced digital manufacturing technology to develop new methods for organ chip manufacturing. They integrated flexible strain sensors with human tissue microarchitectures and developed six different "inks", which then used 3D printing technology to print out the heart chip through a single, continuous manufacturing process. There are many “small wells” on this chip, and each “small well” has independent organization and integrated sensors. With this chip, a variety of heart tissues can be studied.

There are separate organizations and integrated sensors in each "small well".

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