In-depth analysis of the pioneers of non-invasive prenatal testing before Berry and Kang

In 2016, the genetic testing industry continued to grow wildly. The increasing popularity of sequencing concepts, the continuous acceptance of the public, and the exploration of consumption patterns such as genetic + health management have allowed the market to continue to ferment. Accurate medical treatment into the "13th Five-Year Plan", genetic testing was included in the formal supervision, indicating that the genetic testing industry is about to usher in a new era. The first thing that stands out is the field of prenatal testing. In 2015, the non-invasive prenatal testing that was suspended for one year was restarted, and the National Health and Family Planning Commission began to launch a pilot program for non-invasive prenatal testing. In October 2016, the National Health and Family Planning Commission issued a renewed voice, announcing the formal cancellation of the non-invasive prenatal screening and diagnosis pilot, and new regulations for medical institutions and personnel to carry out non-invasive prenatal screening and diagnosis.

The pilot was cancelled, which means the success of clinical exploration of prenatal testing. Non-invasive prenatal testing will be the forerunner of the genetic testing industry and the first to enter the regular force of clinical testing. For a time, the whole industry was enthusiastic, and large and small genetic testing companies poured in. And at the forefront, it is Berry and Kang.

Non-invasive prenatal testing is the core business of Berry and Kang, and is also the focus of sustainable development in 2016.

In February 2016, Berry and Kang released two new products and services for chromosomal disease detection. One is Konoan's chromosomal disease detection, including a package of product solutions from reagents, reagents, and software. The other is Babien's upgrade service for non-invasive DNA prenatal testing, Bebean Plus.

Konoan chromosomal disease detection can be used for aneuploidy variation and chromosome copy number variation greater than 100 Kb, as well as chimeric detection with chimeric ratios above 5%. Not only for prenatal testing, but also for clinicians to investigate abortions and causes of infertility, as well as chromosomal disease detection in patients with suspected chromosomal disorders.

From the perspective of Konoran's product functions, the practical experience of tens of thousands of clinical samples accumulated by Berry and Kang's predecessor services launched in September 2013 provides a basic guarantee for its new products. This time, Konoan's materialized products were launched. It includes a series of complementary products such as DNA extraction, purification, database construction, sequencing, information analysis, report generation, etc. It provides clinicians with a one-stop clinical detection program for DNA detection from DNA extraction to report, allowing doctors to conduct experiments in their own experiments. The room completes this test.

The other product released immediately after the release of Babiant Plus is a comprehensive upgrade of the original product Babiant. Non-invasive prenatal testing products have exploded the traditional Tang screening method with its advantages in accuracy. Babien Plus has again upgraded the traditional non-invasive DNA prenatal testing. In addition to the detection of three major autosomal aneuploidy syndromes (Down's syndrome, Padua's syndrome, Edwards syndrome), a variety of sex chromosome aneuploidy and microdeletion tests have been added. For those families who are extremely concerned about eugenics, it is undoubtedly a new benefit.

Since 2013, the world-famous NIPT (Non-Invasive Production Inspection) services such as Natera, Sequenom, and Illumina have launched detection services for microdeletion microduplication (CNV), with more than one million tests per year. In 2015, Berry and Kang also launched similar testing projects in Hong Kong. In China, maternal intensive age is the social environment of today, and more advanced detection technologies such as NIPT-plus are needed. For families who care about prenatal and postnatal care, the launch of Babiant Plus is the best gift of 2016.

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